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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor (AR)

Anti -Androgen Receptor (AR)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Catalog #A2281-06G
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:10000
Western Blot: 1:1000-1:2000
Immunohistochemistry (Paraffin): 1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10F598
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as liquid, 0.04% sodium azide.
PurityAscites
ImmunogenPurified recombinant fragment of human Androgen Receptor (AR) expressed in E.coli.
SpecificityRecognizes human Androgen Receptor (AR) at 110kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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