You are here:Home
»
Antibodies
»
Abs to Receptors
»
Anti -Androgen Receptor (AR, DHTR, Dihydrotestosterone Receptor, NR3C4, Nuclear receptor subfamily 3 Group C Member 4) (PE)
Anti -Androgen Receptor (AR, DHTR, Dihydrotestosterone Receptor, NR3C4, Nuclear receptor
subfamily 3 Group C Member 4) (PE)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| The Androgen Receptor (Androgen R) is a 90kD steroid hormone receptor that is critical for the development and function of the male reproductive system. Androgen R binding to testosterone or 5a-dihydrotestosterone (DHT) triggers receptor dimerization followed by translocation to the nucleus where it promotes the transcription of androgen-responsive genes. Multiple polymorphisms in Androgen R are linked to the development of prostate cancer. The ligand-binding domain of human Androgen R (aa661-920) shares aa100% sequence identity with mouse and rat Androgen R. | | | Catalog # | A2281-13E | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Hybridoma | Myeloma cells with B cells from Balb/c mice. | | Absorption | 488nm | | Emission | 565-605nm | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2B | | Clone No | 11n6 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant corresponding to aa661-920 from human Androgen R expressed in E. coli (P10275). | | Specificity | Recognizes human Androgen R. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
