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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor, phosphorylated (Ser210)

Anti -Androgen Receptor, phosphorylated (Ser210)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B
Androgen receptor is an androgen-dependent transcription factor involved in prostate cancer cell growth. It is a 110 kD protein and a member of the steroid/nuclear receptor gene superfamily. The PI3K/Akt pathway regulates AR activity by inducing its phosphorylation. Whether AR activity is enhanced or suppressed has been found to be cell line specific(1).
Catalog #A2281-15
ApplicationsWestern blot: please see reference 1
observed size: ~110 kD
positive control: IGF-1 stimulated LNCaP (prostate cancer) cells
Recommended DilutionOptimal dilution to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No4H24
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified
ImmunogenSynthetic peptide containing the serine 210 phosphorylation site of androgen receptor.
SpecificityRecognizes Androgen Receptor, phosphorylated (Ser210)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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