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You are here:Home » Antibodies » Abs to Angiopoietin » Anti -ANGPTL3 (Angiopoietin-like 3, ANG-5, angiopoietin-5, Angiopoietin-related protein 3, ANGPT5, UNQ153/PRO179)

Anti -ANGPTL3 (Angiopoietin-like 3, ANG-5, angiopoietin-5, Angiopoietin-related protein 3,
ANGPT5, UNQ153/PRO179)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E
Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that belongs to the angiopoietin family. It is expressed in the liver and circulates as 70kD, 50kD and 32kD species. These include full length ANGPTL3 as well as the proteolytically separated N- and C-terminal fragments which contain a coiled coil domain and fibrinogen-like domain, respectively. ANGPTL3 promotes an increase in circulating triglyceride levels by directly inhibiting lipoprotein lipase. Mature human ANGPTL3 shares 77% aa sequence identity with mouse ANGPTL3.
Catalog #A2293-48A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA:2-8ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaFusion of a mouse myeloma with B cells obtained from a rat immunized with purified, Sf 21-derived, recombinant human ANGPTL3.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No10K38
HostRat
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified, Sf 21-derived, recombinant human ANGPTL3 (aa19-460; Accession #NP_055310).
SpecificityRecognizes human ANGPTL3. Species sequence homology: mouse (77%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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