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You are here:Home » Antibodies » Abs to Angiopoietin » Anti -Angiopoietin-like 3 (ANGPTL3, ANGPT5)

Anti -Angiopoietin-like 3 (ANGPTL3, ANGPT5)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Angiopoietin-like 3 (ANGPTL3 or ANGPT5), a liver specific protein, is a secreted factor consisting of an N-terminal coiled-coil domain and C-terminal fibrinogen-like domain. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. ANGTPLs (ANGTPL3, ANGPTL4 and ANGPTL6) have a major impact on lipid and possibly glucose metabolism. These proteins also have important effects on plasma triacylglycerol clearance, adipose tissue lipolysis, and adiposity.
Catalog #A2293-48B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:250-1:1000
Optimal dilutions to be determined by the researcher.
HybridomaDerived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ANGPTL3 (243-460aa) protein.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No7G4
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% Thimerosal, before the addition of glycerol to 40%.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human ANGPTL3 (243-460aa) purified from E. coli.
SpecificityRecognizes human ANGPTL3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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