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You are here:Home » Antibodies » Abs to Angiopoietin » Anti -ANGPTL3, NT (Angiopoietin-related Protein 3, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5, UNQ153/PRO179, ANGPT5)

Anti -ANGPTL3, NT (Angiopoietin-related Protein 3, Angiopoietin-like Protein 3,
Angiopoietin-5, ANG-5, UNQ153/PRO179, ANGPT5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Catalog #A2293-48K
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the N-terminal region of human ANGPTL3 (KLH).
SpecificityRecognizes human ANGPTL3. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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