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Abs to Angiopoietin
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Anti -ANGPTL7 (Angiopoietin-related Protein 7, Angiopoietin-like Protein 7, Angiopoietin-like Factor, Cornea-derived Transcript 6 Protein, CDT6, UNQ313/PRO35)
Anti -ANGPTL7 (Angiopoietin-related Protein 7, Angiopoietin-like Protein 7, Angiopoietin-like Factor, Cornea-derived Transcript 6 Protein, CDT6, UNQ313/PRO35)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Angiopoietin-like Factor (ANGPTL7), also known as cornea-derived transcript 6 (CDT6), is a secreted 45kD protein that contains a coiled-coil domain (aa30-110) and a fibrinogen-like domain (aa113-334). ANGPTL7 is expressed in the stromal layer of the cornea, and it forms disulfide-linked homotetramers. It contributes to corneal morphogenesis by suppressing angiogenesis and promoting the deposition of extracellular matrix components. ANGPTL7 is up-regulated in glaucoma and accumulates in the aqueous humor. Mature mouse ANGPTL7 shares 88% and 98% sequence identity with human and rat ANGPTL7. | | | Catalog # | A2293-52E | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Direct ELISA: 0.5-1ug/ml | | Western Blot: 1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS. | | | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to mouse ANGPTL7 expressed in NSO cells (Q8R1Q3). | | Specificity | Recognizes mouse ANGPTL7. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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