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You are here:Home » Antibodies » Abs to Hormones, Steroids » Anti -Angiotensin II (Hypertensin II, Ang II)

Anti -Angiotensin II (Hypertensin II, Ang II)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH IC IF
Ang II plays an important role in regulating natriuretic peptide gene expression during cardiac overload. ANP and BNP gene expression in the rat heart is modulated by the adrenal factors during Ang II-stimulated hemodynamic stress and the AT1 receptor antagonism in NO-deficient hypertension. Moreover, ventricular BNP gene expression in Ang II-induced hypertension in vivo is controlled by post-transcriptional mechanisms and GATA elements.
Catalog #A2295-05
ApplicationsSuitable for use in Immunohistochemistry, Immunocytochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:250-1:16,000
Immunohistochemistry: Frozen and paraffin
PAP, ABC: 1:250-1:16,000
LAB-SA: 1:250-1:16,000
Optimal dilution determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a lyophilized powder. No stabilizing proteins and no preservatives added. Reconstitute with 50ul sterile ddH2O.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa25-32, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH of the human Angiotensin precursor.
SpecificityRecognizes human Angiotensin II. Crossreactivity (RIA)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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