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You are here:Home » Antibodies » Abs to Receptors » Anti -Angiotensin II Type 2 Receptor (AT2) (APC)

Anti -Angiotensin II Type 2 Receptor (AT2) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
AGTR-2, also known as AT2, is a 7 transmembrane domain protein that belongs to the G protein-coupled receptor family 1. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.
Catalog #A2295-07T3
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: Use 10ul to label 10e5 cells.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No8H158
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, 0.1% sodium azide. Labeled with APC.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman AGTR-2-transfected cells
SpecificityRecognizes human AGTR-2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAGTR-2


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