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You are here:Home » Antibodies » Antibodies-Ankyrin » Anti -Ankyrin G (Ankyrin-3, Node of Ranvier, Ankyrin G119, Ankyrin 3, FLJ45464, RP11-369L1.1, Node of Ranvier [ankyrin G], ANK3)

Anti -Ankyrin G (Ankyrin-3, Node of Ranvier, Ankyrin G119, Ankyrin 3, FLJ45464,
RP11-369L1.1, Node of Ranvier [ankyrin G], ANK3)


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Clone Host Grade Applications
Polyclonal Goat Affinity Purified IH
Ankyrin G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin G is also found at sites of epithelial cell- cell contact and in the intracellular membranes of some cells. Ankyrin G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
Catalog #A2295-18A
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 3-5ug/ml. Testing in paraffin-embedded human nerve bundles shows bright staining of axons.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-SWQNETSSGNLE from the intermal region of human Ankyrin G (NP_066267.2; NP_001140.2). Species sequence homology: bovine, mouse and rat.
SpecificityRecognizes human Ankyrin G.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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