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You are here:Home » Antibodies » Abs to Ankyrin » Anti -Ankyrin Repeat Domain 28 (ANKRD28, ANKRD-28, PITK, Phosphatase Interactor Targeting K Protein)

Anti -Ankyrin Repeat Domain 28 (ANKRD28, ANKRD-28, PITK, Phosphatase Interactor Targeting
K Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
PITK was previously identified as a novel PP1 targeting subunit implicated in modulating the phosphorylation of the transcriptional regulator heterogeneous nuclear ribonucleoprotein K (hnRNP K). Through the phosphorylation of PITK at S1013 and S1017 (residues that flank or reside within a PP1C-binding motif), the binding of the PP1 catalytic subunit to PITK, and subsequently the activity of the holoenzyme, are discretely controlled.
Catalog #A2295-19L
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormTris-buffered Saline and 0.1% BSA
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide mapping to a region between residue 975 and 1025 of human ankyrin repeat domain 28 (phosphatase interactor targeting K protein) using the numbering given in entry NP_056014.2 (GeneID 23243).
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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