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You are here:Home » Molecular Biology » MB-Annexin » Annexin II, p11, Positive Control

Annexin II, p11, Positive Control

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Specifications

p11 is the light chain component of the Calpactin complex and a member of the S100 family of proteins that can form a heterotetramer. The functional complex is formed by the interaction of two heavy chains (annexin II) and two light chains (p11). It is important for many cellular processes, including Ca2+-dependent exocytosis, non-constitutive secretory pathways, and the correct trafficking vesicles as well as proteins out of the cell. Recently, p11 was shown to be the critical component involved in the plasma membrane translocation of NAV1.8, a subunit of the tetrodotoxin-resistant sodium channel found in sensory neurons.
Catalog #A2295-24A
Sequence (linear) (rat) CNQKDPLAVDK-CONH2
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHuman, synthetic peptide
Purity~90%
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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