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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -Anterior Gradient 2, ID (Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2, UNQ515/PRO1030)

Anti -Anterior Gradient 2, ID (Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8,
Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2, UNQ515/PRO1030)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
AG-2 (Anterior gradient protein 2; also AGR2, GOB4 and HPC8) is an 18-21kD member of the PDI family of enzymes. It is expressed in secretory cell types, such as prostate epithelium, small intestine goblet, Paneth and enteroendocrine cells, and multiple carcinoma cell types. Although AG-2 possesses a signal sequence, it appears to be rarely secreted, instead being found in the ER due the presence of a KTEL ER retention signal at its C-terminus. AG-2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Mature human AG-2 is 155aa in length (aa21-175). Cys81 is presumed to participate in intermolecular bond formation. There is one potential alternative start site 20aa upstream of the standard start site.
Catalog #A2296-82F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 1:128,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-GAKKDTKDSRPK from an internal region of human AGR2.
SpecificityRecognizes human AGR2. Species sequence homology: Canine and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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