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Anti -APH1A, ID (Gamma-secretase Subunit APH-1A, APH-1a, Aph-1alpha, Presenilin-stabilization Factor, PSF, CGI-78, UNQ579/PRO1141)
Anti -APH1A, ID (Gamma-secretase Subunit APH-1A, APH-1a, Aph-1alpha,
Presenilin-stabilization Factor, PSF, CGI-78, UNQ579/PRO1141)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198). | | | Catalog # | A2296-83D | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:128,000 | | Western Blot: 0.05-0.1ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide C-HVTDRSDARLQYG from an internal region of human APH1A. | | Specificity | Recognizes human APH1A. Species sequence homology: bovine, canine, mouse, porcine and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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