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You are here:Home » Biochemicals » Biochem-Antibiotics » Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010)

Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010)


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Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease.
Catalog #A2297-30
Purity >95% by HPLC
Solubility Soluble in ethanol, methanol, DMF or DMSO.
CAS Number154639-24-4(TAN1364B)
Molecular FormulaC21H36O5
Molecular Weight368.5
SourceStreptomyces sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAntibiotic TAN 1364B, Antibiotic CI 010

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