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Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010)
Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010)
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| Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease. | | | Catalog # | A2297-30 | | Purity | >95% by HPLC | | Solubility | Soluble in ethanol, methanol, DMF or DMSO. | | CAS Number | 154639-24-4 (TAN 1364B) | | Molecular Formula | C21H36O5 | | Molecular Weight | 368.5 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Antibiotic TAN 1364B, Antibiotic CI 010 |
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