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You are here:Home » Molecular Biology » MB-Protease Inhibitors » a1-Antichymotrypsin, Recombinant Human, His-tag, aa24-423 (Alpha-1-Antichymotrypsin, AACT, ACT, Growth Inhibiting Protein 24, GIG24, Growth Inhibiting Protein 25, GIG25, Serpin Peptidase Inhibitor Clade A (alpha-1 Antiproteinase, Antitrypsin) Member 3, SE

a1-Antichymotrypsin, Recombinant Human, His-tag, aa24-423 (Alpha-1-Antichymotrypsin, AACT,
ACT, Growth Inhibiting Protein 24, GIG24, Growth Inhibiting Protein 25, GIG25, Serpin
Peptidase Inhibitor Clade A (alpha-1 Antiproteinase, Antitrypsin) Member 3, SE

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Specifications

Alpha-1-antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. Recombinant alpha-1-antichymotrypsin protein was expressed in E. coli and purified by using conventional chromatography techniques.
Catalog #A2298-01T
SourceRecombinant corresponding to human Alpha-1-antichymotrypsin, his-tagged, expressed in E. coli.
AA sequenceMGSSHHHHHH SSGLVPRGSH MHPNSPLDEE NLTQENQDRG THVDLGLASA NVDFAFSLYK QLVLKAPDKN VIFSPLSIST ALAFLSLGAH NTTLTEILKG LKFNLTETSE AEIHQSFQHL LRTLNQSSDE LQLSMGNAMF VKEQLSLLDR FTEDAKRLYG SEAFATDFQD SAAAKKLIND YVKNGTRGKI TDLIKDLDSQ TMMVLVNYIF FKAKWEMPFD PQDTHQSRFY LSKKKWVMVP MMSLHHLTIP YFRDEELSCT VVELKYTGNA SALFILPDQD KMEEVEAMLL PETLKRWRDS LEFREIGELY LPKFSISRDY NLNDILLQLG IEEAFTSKAD LSGITGARNL AVSQVVHKAV LDVFEEGTEA SAATAVKITL LSALVETRTI VRFNRPFLMI IVPTDTQNIF FMSKVTNPKQ A
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~47.6kD
SourceE.coli
Purity~95% (SDS-PAGE) Purified by immunoaffinity chromatography.
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol 1mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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