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You are here:Home » Antibodies » Abs to Apoptosis » Anti -Apaf-1 (Apoptosis Protease Activating Factor 1)

Anti -Apaf-1 (Apoptosis Protease Activating Factor 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Catalog #A2298-64A
ApplicationsWestern Blotting: 1:1000-1:2000
Optimal working dilutions to be determined by researcher.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS with 0.02% sodium azide.
PurityPurified IgG prepared by affinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acids 12-28 of human Apaf1.
SpecificityApaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Recognizes a 130kD band in Western blots. Species Crossreactivity: Human, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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