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You are here:Home » Antibodies » Abs to Proteins » Anti -APC (Adenomatous Polyposis coli, Protein APC)

Anti -APC (Adenomatous Polyposis coli, Protein APC)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B IF
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Catalog #A2298-70A1
ApplicationsSuitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:5,000
Immunoflurorescence: 1:100-1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10K108
HostRat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to amino acids 2170-2394 of mouse APC
SpecificityRecognizes mouse APC.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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