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Anti -APC (Adenomatous Polyposis coli, Protein APC)
Anti -APC (Adenomatous Polyposis coli, Protein APC)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E B IF |
|
| This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. | | | Catalog # | A2298-70A1 | | Applications | Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:5,000 | | Immunoflurorescence: 1:100-1:1,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10K108 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant protein corresponding to amino acids 2170-2394 of mouse APC | | Specificity | Recognizes mouse APC. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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