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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -ANAPC1 (Anaphase-promoting Complex Subunit 1, APC1, Cyclosome Subunit 1, Mitotic Checkpoint Regulator, Testis-specific Gene 24 Protein, TSG24)

Anti -ANAPC1 (Anaphase-promoting Complex Subunit 1, APC1, Cyclosome Subunit 1, Mitotic
Checkpoint Regulator, Testis-specific Gene 24 Protein, TSG24)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle. This is one of a number of novel phosphorylation sites for APC1 identified in Kraft C et al. It may be involved in the regulation of the APC/C.
Catalog #A2298-70H1
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human ANAPC1 at N-terminal.
SpecificityRecognizes human ANAPC1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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