Anti -APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog,
Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| CDC16 is located at the centrosome and mitotic spindle where it co-localizes with CDC27 and is required for maintaining core stability in the spindle checkpoint pathway. It functions as a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. | | | Catalog # | A2298-72L4 | | Applications | Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 5ug/ml | | ELISA: 1:10,000 | | Western Blot: 1:500-1:3,000 | | Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa sequence 575-588 of human CDC16 protein. | | Specificity | Recognizes human CDC16. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Anaphase Promoting Complex Subunit 6, CDC16 (Cell Division Cycle 16 S. cerevisiae Homolog), CDC16 Protein |
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