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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog, Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)

Anti -APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog,
Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
CDC16 is located at the centrosome and mitotic spindle where it co-localizes with CDC27 and is required for maintaining core stability in the spindle checkpoint pathway. It functions as a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
Catalog #A2298-72L4
ApplicationsSuitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 5ug/ml
ELISA: 1:10,000
Western Blot: 1:500-1:3,000
Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa sequence 575-588 of human CDC16 protein.
SpecificityRecognizes human CDC16.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAnaphase Promoting Complex Subunit 6, CDC16 (Cell Division Cycle 16 S. cerevisiae Homolog), CDC16 Protein


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