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Anti -APC10 (Anaphase Promoting Complex 10, ANAPC10, DKFZP564L0562, DOC1)
Anti -APC10 (Anaphase Promoting Complex 10, ANAPC10, DKFZP564L0562, DOC1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| APC is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds 1/Cut 2 and cyclin B. It was found that APC 10/Doc 1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid body in telophase and cytokinesis. These results strongly support the notion that human APC 10/Doc 1 may be one of the APC core subunits rather than the transiently associated regulatory factor. | | | Catalog # | A2298-72N | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | 0.01% Sodium Azide; 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7 | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: GADPKQLERTG, corresponding to amino acids 10-20 of Human APC10. | | Specificity | This antibody detects a band at about 26kD that corresponds to Apc10. Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse (100% identity with immunogen) due to sequence homology. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Anaphase Promoting Complex Subunit 10 |
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