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You are here:Home » Antibodies » Abs to Enzymes, Endonuclease » Anti -APEX1, NT (DNA-(apurinic or apyrimidinic site) lyase, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APEX nuclease, APEN, Protein REF-1, APEX1, APE, APEX, APX, HAP1, REF1)

Anti -APEX1, NT (DNA-(apurinic or apyrimidinic site) lyase, Apurinic-apyrimidinic
endonuclease 1, AP endonuclease 1, APEX nuclease, APEN, Protein REF-1, APEX1, APE, APEX,
APX, HAP1, REF1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This protein is the major AP endonuclease in human cells.
Catalog #A2298-74C1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the N-terminal region of human APEX1 (KLH).
SpecificityRecognizes human APEX1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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