Anti -APEX1 (DNA-(apurinic or apyrimidinic site) lyase, Apurinic-apyrimidinic endonuclease
1, AP endonuclease 1, APEX nuclease, APEN, Protein REF-1, APEX1, APE, APEX, APX, HAP1,
REF1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Catalog # | A2298-74C7 | | Human A (MW | 38kD) endonuclease-1 (HAP-1), also known as APE, APEX or Ref-1, is a nuclear enzyme that repairs apurinic/apyramidinic sites in cellular DNA. Human AP endonucleases-1 cleaves the phosphodiesterase followed by filling-in of the nucleotide gap by DNApolymerase. HAP-1 has been detected in a wide range of human tissues including bladder, breast, small and large intestine, lung, ovary, pancreas, skin, spleen, testis, thymus and thyroid. | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 2.5-5ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | HepG2 cells. Tonsil | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to human AP endonuclease 1. | | Specificity | Recognizes human APE-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -APEX1 (DNA-(apurinic or apyrimidinic site) lyase, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APEX nuclease, APEN, Protein REF-1, APEX1, APE, APEX, APX, HAP1, REF1) |
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