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You are here:Home » Antibodies » Abs to Enzymes » Anti -APE-1 (Apurinic Endonuclase Factor 1)

Anti -APE-1 (Apurinic Endonuclase Factor 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
APE1 repairs oxidative DNA damages in vitro. It may also play a role in preventing cell death by suppressing mutations. APE1 removes the blocking groups from the 3'-termini of breaks in the DNA strand generated by ionizing radiation or bleomycin. APE1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effects of oxidizing agents.
Catalog #A2298-74E1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (KLH). within residues 200-250 of human APE1 protein (Swiss Prot: P27695).
SpecificityRecognizes endogenous levels of human APE1 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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