Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Endonuclease » Anti -APE (APEX, APEX1, APEX Nuclease Multifunctional DNA Repair Enzyme, APX, APE1, APEN, HAP1, REF1, REF-1, AP Lyase, AP Endonuclease Class I, DNA Apurinic/Apyrimidinic Exonuclease/Lyase)

Anti -APE (APEX, APEX1, APEX Nuclease Multifunctional DNA Repair Enzyme, APX, APE1, APEN,
HAP1, REF1, REF-1, AP Lyase, AP Endonuclease Class I, DNA Apurinic/Apyrimidinic
Exonuclease/Lyase)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Catalog #A2298-74L2
ApplicationsSuitable for use in Dot Blot and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8D107
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 7.4, 1% BSA and 0.05% sodium azide.
PurityPurified using Protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (~95%) fetal bovine serum.
ImmunogenPartial sequence of recombinant full-length protein to human APEX1
SpecificityRecognizes human APEX1. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links