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Anti -Atg7 (Autophagy Protein 7, Ubiquitin-activating enzyme E1-like protein, hAGP7, APG7-like, ATG7, APG7L)
Anti -Atg7 (Autophagy Protein 7, Ubiquitin-activating enzyme E1-like protein, hAGP7,
APG7-like, ATG7, APG7L)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH IF |
|
| Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. Subunit: Homodimer (By similarity). Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. In yeast, ATG7 appears to be required for fusion of peroxisomal and vaculuolar membranes. Belongs to the ATG7 family. | | | Catalog # | A2298-74R | | Domain | The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12. | | Tissue specificity | Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. | | Applications | Suitable for use in Immunofluorescence and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: 1:200-1:3000 | | Immunofluorescence: 1:200-1:3000 | | Optimal dilutions to be determined by the researcher. . | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to the C-terminal of human APG7 protein conjugated to blue carrier protein. CELLULAR LOCAlizaTION: Cytoplasm (Probable). | | Specificity | Recognizes human ATG7. Species crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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