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You are here:Home » Antibodies » Abs to Autophagy » Anti -Atg4C (Apg4c, Autl3, Cysteine Protease ATG4C, Autophagy-related Protein 4 Homolog C, Autophagin-3, Autophagy-related Cysteine Endopeptidase 3, AUT-like 3 Cysteine Endopeptidase)

Anti -Atg4C (Apg4c, Autl3, Cysteine Protease ATG4C, Autophagy-related Protein 4 Homolog C,
Autophagin-3, Autophagy-related Cysteine Endopeptidase 3, AUT-like 3 Cysteine
Endopeptidase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Catalog #A2298-74V4
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ENZYME REGULATION Inhibited by N-ethylmaleimide.
Cellular LocalizationCytoplasm (Probable).
Tissue SpecificityHighly expressed in skeletal muscle, heart, liver and testis. Belongs to the peptidase C54 family.
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
FormSupplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material.
PuritySerum
ImmunogenSynthetic peptide corresponding to the C-terminal of human ATG4C protein conjugated to Blue Carrier Protein. The peptide is homologous with the corresponding sequence derived from ATG4C protein in mouse and rat.
SpecificityRecognizes human ATG4C. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAutophagin-3, Autophagy-related cysteine endopeptidase 3, AUT-like 3 cysteine endopeptidase


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