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Anti -Atg4C (Apg4c, Autl3, Cysteine Protease ATG4C, Autophagy-related Protein 4 Homolog C, Autophagin-3, Autophagy-related Cysteine Endopeptidase 3, AUT-like 3 Cysteine Endopeptidase)
Anti -Atg4C (Apg4c, Autl3, Cysteine Protease ATG4C, Autophagy-related Protein 4 Homolog C,
Autophagin-3, Autophagy-related Cysteine Endopeptidase 3, AUT-like 3 Cysteine
Endopeptidase)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| Catalog # | A2298-74V4 | | Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ENZYME REGULATION | Inhibited by N-ethylmaleimide. | | Cellular Localization | Cytoplasm (Probable). | | Tissue Specificity | Highly expressed in skeletal muscle, heart, liver and testis. Belongs to the peptidase C54 family. | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Form | Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to the C-terminal of human ATG4C protein conjugated to Blue Carrier Protein. The peptide is homologous with the corresponding sequence derived from ATG4C protein in mouse and rat. | | Specificity | Recognizes human ATG4C. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Autophagin-3, Autophagy-related cysteine endopeptidase 3, AUT-like 3 cysteine endopeptidase |
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