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You are here:Home » Antibodies » Abs to Autophagy » Anti -APG12L (ATG12, Ubiquitin-like Protein ATG12, Autophagy-related Protein 12, APG12-like, APG12)

Anti -APG12L (ATG12, Ubiquitin-like Protein ATG12, Autophagy-related Protein 12,
APG12-like, APG12)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. APG12L is the human homologue of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy. The protein possesses 27% identity and 48% similarity with the yeast APG12p. Northern blot analysis confirms the ubiquitous expression of the protein in human tissues. The gene encoding human APG12L protein is localized on chromosome 5q21-q22.
Catalog #A2298-76D1
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa84-101 (SAAVSPGTEEPAGDTKKK) of human APG12L.
SpecificityRecognizes human APG12L. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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