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Anti -APG12L (ATG12, Ubiquitin-like Protein ATG12, Autophagy-related Protein 12, APG12-like, APG12)
Anti -APG12L (ATG12, Ubiquitin-like Protein ATG12, Autophagy-related Protein 12,
APG12-like, APG12)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. APG12L is the human homologue of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy. The protein possesses 27% identity and 48% similarity with the yeast APG12p. Northern blot analysis confirms the ubiquitous expression of the protein in human tissues. The gene encoding human APG12L protein is localized on chromosome 5q21-q22. | | | Catalog # | A2298-76D1 | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:100-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.025% sodium azide, 50% glycerol. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa84-101 (SAAVSPGTEEPAGDTKKK) of human APG12L. | | Specificity | Recognizes human APG12L. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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