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You are here:Home » Antibodies » Abs to Autophagy » Anti -Apg12 (Autophagy-related 12, 4931423H11Rik, A330058M13Rik, Atg12, Apg12L, APG12-like, Atg12L, Autophagy-related protein 12)

Anti -Apg12 (Autophagy-related 12, 4931423H11Rik, A330058M13Rik, Atg12, Apg12L,
APG12-like, Atg12L, Autophagy-related protein 12)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. APG12 is the human homolog of a yeast protein involved in autophagy. APG12 is conjugated to APG5. The APG12-ATG5 conjugate has an apparent molecular mass of 65kD. The C-terminal glycine of APG12 is conjugated to a central lysine (lys130) of APG5. Studies showed that overexpression of APG3 facilitated formation of the APG12-APG5 conjugate, suggesting that APG3 cross-talks with the APG12 conjugation system. APG12 is ubiquitously expressed.
Catalog #A2298-76P
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionOptimal dilution determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G313
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenFull recombinant human APG12, isoform 2, (1-74) with a GST tag.
SpecificityRecognizes human Atg12.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAutophagy-related protein 12, GENE NAMEs: ATG12, APG12, APG12L


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