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You are here:Home » Antibodies » Abs to Enzymes, Cytidine Deaminase (APOBEC) » Anti -Apobec1, NT (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1, ABEDP, CDAR1, HEPR, Apolipoprotein B mRNA Editing Enzyme)

Anti -Apobec1, NT (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1, ABEDP,
CDAR1, HEPR, Apolipoprotein B mRNA Editing Enzyme)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36aa peptide. The exon 2-skipped transcript accounts for approximately 50% of APOBEC1 mRNA in the adult small intestine and up to 90% of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract.
Catalog #A2298-88A4
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human Apobec1 (KLH).
SpecificityRecognizes human Apobec1. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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