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You are here:Home » Antibodies » Abs to Enzymes, Cytidine Deaminase (APOBEC) » Anti -APOBEC2 (Probable C->U-editing Enzyme APOBEC-2)

Anti -APOBEC2 (Probable C->U-editing Enzyme APOBEC-2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Catalog #A2298-88P
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 1-3ug/ml, observed in human skeletal muscle lysates on ~26kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KPQDFEYVWQN, from human APOBEC2, at the internal region of the protein (NP_006780.1).
SpecificityRecognizes human APOBEC2. Species sequence homology: Bovine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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