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Anti -Apolipoprotein A-I (Apolipoprotein A-I Precursor, Apolipoprotein AI, Apo AI, Apo A-I, ApoA-I, Apo-AI, Apolipoprotein A1, APOA1, Ltw-1, Lvtw-1, MGC117399)
Anti -Apolipoprotein A-I (Apolipoprotein A-I Precursor, Apolipoprotein AI, Apo AI, Apo
A-I, ApoA-I, Apo-AI, Apolipoprotein A1, APOA1, Ltw-1, Lvtw-1, MGC117399)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH IC Gel |
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| Apolipoprotein AI promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein AI is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77aa; an 18aa signal peptide is removed co-translationally and a 6aa propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. | | | Catalog # | A2299-12M | | Applications | Suitable for use in ELISA, Dot Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000; use on native and denatured human ApoA1. | | Dot Blot: Use on native and denatured human ApoA1. | | Immunohistochemistry (Frozen): 1:40 | | Immunocytochemistry: Cultured human cells | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a lyophilized powder from PBS, mannitol. Reconstitute with 1ml sterile ddH2O. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Human Apolipoprotein AI. | | Specificity | Recognizes human Apolipoprotein AI (apoAI) at ~28kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | APOA1/APOC3 Fusion Gene |
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Download Specifications for Anti -Apolipoprotein A-I (Apolipoprotein A-I Precursor, Apolipoprotein AI, Apo AI, Apo A-I, ApoA-I, Apo-AI, Apolipoprotein A1, APOA1, Ltw-1, Lvtw-1, MGC117399) |
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