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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -Apolipoprotein B (Apo B)

Anti -Apolipoprotein B (Apo B)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E
Apolipoprotein B plays an essential role in lipid transport and metabolism. Apo B may regulate cholesterol synthesis through its interaction with specific cell membrane receptors and by inhibition of HMG Co A reductase. This enzyme has been identified as the rate controlling enzyme in cholesterol biosynthesis. Apo B may be important in the genesis of atherosclerosis. Apo B is the major protein moiety of all lipoproteins other than high density lipoprotein (HDL) in plasma. Increased levels of apo B100 are associated with an increased risk of coronary artery disease.
Catalog #A2299-38
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Affinity Constant5.0x10e7 L/mole
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1b
Clone No8.F.16
HostMouse
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
PurityPurified IgG by DEAE chromatography.
ImmunogenHuman low density lipoprotein.
SpecificityRecognizes human Apolipoprotein B. Does not crossreact with Apolipoprotein A-I or Apolipoprotein A-II.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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