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Anti -Apolipoprotein C-II (Apo C-II) (Biotin)
Anti -Apolipoprotein C-II (Apo C-II) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| Apolipoprotein C2 (ApoC2/II) is a 8-9kD, secreted member of the Apolipoprotein C2 family of proteins. It is produced by hepatocytes and represents a major component of VLDL particles. It activates lipoprotein lipase and may self-associate to form amyloid-type fibrils. The human ApoC2 precursor is 101 amino acids (aa) in length. It contains a 22 amino acid (aa) signal sequence, followed by a 79 aa ProApoC2 that contains a lipid-binding region (aa 43-51) and an enzyme interaction site (aa 55-78). ProApoC2 represents > 90% of circulating ApoC2. In human, limited proteolytic processing occurs with removal of the six aa prosegment (aa 23-28). This does not affect activity. Human ProApoC2 is 59% aa identical to mouse and dog ProApoC2, respectively. | | | Catalog # | A2299-64B | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.25ug/mL | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in PBS containing 50ug of bovine serum albumin (BSA). Label with (Biotin) Reconstitute with 200ul 40-50% glycerol, TBS, 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | | Immunogen | E. coli-derived recombinant human Apolipoprotein C2. (aa 23 - 101) | | Specificity | Recognizes human Apolipoprotein C2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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