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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -Apolipoprotein C-III (Apo C-III)

Anti -Apolipoprotein C-III (Apo C-III)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL).
Catalog #A2299-69C
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia.
ApplicationsSuitable for use in ELISA, Western Blot, Enzyme Conjugation, or Biotinylation. Other applications not tested.
Recommended DilutionELISA: 1:200-1:40,000
Western Blot: 1:200-1:40,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 75mM PBS, pH 7.2, 0.5mM EDTA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenPurified human Apolipoprotein CIII
SpecificityRecognizes human Apolipoprotein CIII (Apo CIII).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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