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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -Apolipoprotein E (Apo E)

Anti -Apolipoprotein E (Apo E)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Catalog #A2299-73E
ApplicationsSuitable for use in ELISA, Western Blot, Immunodiffusion, Radial Immunodiffusion and Immunoelectrophoresis. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500-1:1000
Radial Immunodiffusion: 1:40
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot Determined
FormSupplied as a liquid, 0.05% sodium azide.
PuritySerum
ImmunogenFull length purified mouse Apolipoprotein E from pooled mouse plasma high and very low density lipoproteins.
Cellular LocalizationSecreted.
SpecificityRecognizes mouse Apolipoprotein E (Apo E). No data available regarding reactivity with rat. Exremely low recognition of human ApoE; cross-reactivity with human has not been conclusively tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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