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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum E B

Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Catalog #	A2299-73E
Applications	Suitable for use in ELISA, Western Blot, Immunodiffusion, Radial Immunodiffusion and Immunoelectrophoresis. Other applications not tested.
Recommended Dilutions	Western Blot: 1:500-1:1000
	Radial Immunodiffusion: 1:40
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Mouse
Concentration	Not Determined
Form	Supplied as a liquid, 0.05% sodium azide.
Purity	Serum
Immunogen	Full length purified mouse Apolipoprotein E from pooled mouse plasma high and very low density lipoproteins.
Cellular Localization	Secreted.
Specificity	Recognizes mouse Apolipoprotein E (Apo E). No data available regarding reactivity with rat. Exremely low recognition of human ApoE; cross-reactivity with human has not been conclusively tested.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.