Anti -Apolipoprotein E (Apolipoprotein-E, Apo E, ApoE, Apo-E, Alzheimer Disease 2, AD2,
Apolipoprotein E3, APOE3, Apoprotein, LDLCQ5, LPG, MGC1571)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E IH IC Gel |
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| The apolipoproteins are family of amphipathic lipoproteins that plays a crucial role in lipid metabolism. In particular, apolipoprotein E (apo E) is a major component of high density lipoproteins (HDL) chylomicrons and very low-density lipoprotein (VLDL), which functions to remove excess cholesterol. Apo E mediates lipid metabolism and cholesterol homeostasis by binding to several hepatic lipoprotein receptors, such as low density lipoprotein receptor (LDLR) and the LDLR-related protein (1). Apo E deficiency is linked to hyperlipoproteinemia type III; a genetic disorder characterized by elevated plasma cholesterol and triglyceride levels and accelerated coronary artery disease (2). Three major isoforms of Apo E (E2, E3, E4) have been identified, with E3 being the most common in human. E4 presence has been associated to increase probability of developing late-onset form of Alzheimer disease (3). | | | Catalog # | A2299-74K | | Applications | Suitable for use in ELISA, Dot Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000 on native and denatured human apoE. | | Dot Blot: native and denatured human apoE. | | Immunohistochemistry (Frozen): 1:30 | | Immunocytochemistry: Cultured human cells. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute with 1ml sterile ddH2O. | | Purity | Purified | | Immunogen | Human Apolipoprotein E from plasma. | | Specificity | Recognizes human Apolipoprotein E at ~34kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Apolipoprotein E (Apolipoprotein-E, Apo E, ApoE, Apo-E, Alzheimer Disease 2, AD2, Apolipoprotein E3, APOE3, Apoprotein, LDLCQ5, LPG, MGC1571) |
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