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You are here:Home » Antibodies » Abs to Receptors » Anti -Apolipoprotein E Receptor 2 (APOER2, HSZ75190, Low Density Lipoprotein Receptor-related Protein 8, LRP8, MCI1)

Anti -Apolipoprotein E Receptor 2 (APOER2, HSZ75190, Low Density Lipoprotein
Receptor-related Protein 8, LRP8, MCI1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Apolipoprotein E receptor 2 (ApoER2) is an NMDA associated protein found in neurons. It participates in important functions from guiding neurons in the embryonic brain to regulating synaptic signaling. It is also involved in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.
Catalog #A2299-75S
Cellular Localization Type I membrane. Isoforms that contain the exon encoding for a furin-cleavage site are proteolytically processed, leading to a secreted receptor fragment.
Positive Control Mouse brain membrane preparation
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-glycine and 150mM NaCl
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide made to a C-terminal portion of the human ApoER2 protein sequence (between residues 863-963). Homology: 100% chicken, 95% mouse
SpecificityThis antibody is specific for ApoER2. Species Crossreactivity: This antibody reacts with mouse ApoER2 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesLow-density Lipoprotein Receptor-related Protein 8


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