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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -APOF (Apolipoprotein F, Apo-F, Lipid Transfer Inhibitor Protein, LTIP)

Anti -APOF (Apolipoprotein F, Apo-F, Lipid Transfer Inhibitor Protein, LTIP)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Apolipoprotein F (Apo F), also known as lipid transfer inhibitor protein (LTIP) based on its ability to inhibit lipid transfer between lipoproteins, is a protein component of several lipoprotein classes and a physiologic regulator of cholesteryl ester transfer protein (CETP) function. Apo F activity was reported to be localized to LDL, consistent with its greater inhibitory activity on this lipoprotein. Apo F activity is controlled by its reversible incorporation into an inactive complex which provides for short-term fine-tuning of lipoprotein remodeling mediated by CETP. ApoF overexpression reduces HDL cholesterol levels by increasing clearance of HDL-CE.ApoF may be an important determinant of HDL metabolism and reverse cholesterol transport.
Catalog #A2299-76V4
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Immunohistochemistry (Paraffin): 2.5-3.8ug/ml
Western Blot: 0.3-1ug/ml, observed in human liver lysates on ~35kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KSYDLDPGAGSLE, from human APOF, at C-terminal (NP_001629.1).
SpecificityRecognizes human APOF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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