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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein E3, Alzheimer Disease 2 (APOE*E4-associated, late onset)

Anti -Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein
E3, Alzheimer Disease 2 (APOE*E4-associated, late onset)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Purified E
Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increase amounts of the protein are found at sites or peripheral nerve injury and regeneration. A mutant form is associated with familial type hyperlipoproteinemia.
Catalog #A2299-76Z
Human Apo E is not easy to isolate and purify, but rabbit Apo E can be obtained in large amounts. The human aa sequence of Apo E3 is about 80% homologous to that of rabbit Apo E, hence it is possible to use the rabbit apolipoprotein to raise antibodies to human Apo E.
ApplicationsSuitable for use in ELISA. Other applications not tested
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Numbern/a
Clone TypePolyclonal
HostGoat
SourceRabbit
ConcentrationAs reported
FormSupplied as a liquid in 50mM Tris, 0.15M sodium chloride, 1mM EDTA, 0.01% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenRabbit Apolipoprotein E.
SpecificityApolipoprotein E (Apo E)Recognizes rabbit Apolipoprotein E. Species sequence homology: human (80%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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