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You are here:Home » Antibodies » Abs to Apoptosis » Anti -Apoptosis Antagonizing Transcription Factor (AATF, CHE1, CHE-1, DED, HSPC277, Protein AATF, Rb-binding protein Che-1)

Anti -Apoptosis Antagonizing Transcription Factor (AATF, CHE1, CHE-1, DED, HSPC277,
Protein AATF, Rb-binding protein Che-1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Catalog #A2299-90U
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 2-5ug/mg lysate.
Immunoprecipitation: 2-5ug/mg lysate.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized by this antibody maps to a region between residue 125 and 175 of human apoptosis antagonizing transcription factor (Che-1) using the numbering given in entry NP_036270.1 (GeneID 26574).
SpecificitySpecies Crossreactivity: Human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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