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You are here:Home » Antibodies » Abs to Proteins » Anti -Aprataxin (APTX)

Anti -Aprataxin (APTX)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Catalog #A2299-97D
ApplicationsSuitable for use in Western Blot and Immunoprecipitation,. Other applications not tested.
Recommended DilutionImmunoprecipitation: 1-4ug/mg lysate
Western Blot: 1:10,000- 1:25,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide mapping to a region between residues 100 and 150 of human Aprataxin using the numbering given in SwissOrot entry Q7Z2E3 (GeneID 54840).
SpecificityRecognizes human Aprataxin protein. Reaction with mouse is unlikely.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAOA1, Ataxia-oculomotor apraxia syndrome 1, FHA-HIT, Forkhead-associated domain histidine-triad like protein, EOAHA, early onset with hypoalbuminemia


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