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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified B IP

This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Catalog #	A2299-97D
Applications	Suitable for use in Western Blot and Immunoprecipitation,. Other applications not tested.
Recommended Dilution	Immunoprecipitation: 1-4ug/mg lysate
	Western Blot: 1:10,000- 1:25,000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	~1mg/ml
Form	As reported
Purity	Purified by immunoaffinity chromatography.
Immunogen	A synthetic peptide mapping to a region between residues 100 and 150 of human Aprataxin using the numbering given in SwissOrot entry Q7Z2E3 (GeneID 54840).
Specificity	Recognizes human Aprataxin protein. Reaction with mouse is unlikely.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	AOA1, Ataxia-oculomotor apraxia syndrome 1, FHA-HIT, Forkhead-associated domain histidine-triad like protein, EOAHA, early onset with hypoalbuminemia