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Anti -APRIL (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13)
Anti -APRIL (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related
Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IP IH IC FC |
|
| APRIL (a proliferation-inducing ligand) is a newly identified member of the tumor necrosis factor (TNF) family. Ectopic expression of APRIL is associated with the upregulation of X-linked inhibitor of apoptosis protein (XIAP) and may act as antiapoptotic factor. Although transcripts of APRIL are of low abundance in normal tissues, high levels of mRNA are detected in transformed cell lines, and in human cancers of colon, thyroid, and lymphoid tissues in vivo. | | | Catalog # | A2299-98H | | Applications | | | Suitable for use in Flow Cytometry, Immunocytochemistry | | Immunohistochemistry, Immunoprecipitation | | and Western Blot. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: Paraffin sections | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6D126 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified (95% SDS-PAGE). | | | Immunogen | Recombinant corresponding to aa 93-233 of human APRIL. | | Specificity | Recognizes human APRIL and TWE-PRIL. Does not cross-react with mouse APRIL and TWE-PRIL. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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