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Anti -Aquaporin 1 (AQP1, CHIP-28, Channel-forming Integral Protein)
Anti -Aquaporin 1 (AQP1, CHIP-28, Channel-forming Integral Protein)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IP IH IF |
|
| Aquaporin 1 is a 28kD integral protein thought at first to be a breakdown product of the Rh polypeptide but was later shown to be a unique molecule that is abundant in erythrocytes and renal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | | | Catalog # | A3000-01B | | Applications | Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunofluorescence. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000-1:20,000 | | Western Blot: 1:1000-1:5000; Predicted molecular weight 32.3kD. | | Immunoprecipitation: 1:1000 | | Immunohistochemistry (Frozen): 1:500-1:1000 | | Immunohistochemistry (Paraffin): 1:500-1:1000 Heat mediated antigen retrieval is required for paraffin sections. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Kidney | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 8J300 | | Host | Mouse | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid, 1% BSA, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide, corresponding to aa249-269 of rat Aquaporin 1. Cellular Localization: Plasma membrane. | | Specificity | Recognizes an epitope within the cytoplasmic domain of the water-specific channel of rat Aquaporin 1. Species Crossreactivity: human, mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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