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You are here:Home » Antibodies » Abs to Lectins » Anti -Arachis hypogaea (PNA, Peanut Agglutinin) (Biotin)

Anti -Arachis hypogaea (PNA, Peanut Agglutinin) (Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified IH
Lectins are derived from the extracts of plants, animals, viruses and microorganisms and are known to agglutinate red blood cells. These agglutinins can select cell types according to blood group activities utilizing sugar-binding mechanisms.
Catalog #A3305-36
Lectins form precipitates with glycoconjugates and are useful for identifying or separating oligosaccharides with identical sugar compositions such as galactose, mannose or glucose.
Arachis hypogaea (PNA, Peanut Agglutinin), 110kD, is composed of four identical subunits of approximately 27kD each. It is galactose-specific, with strong anti-T-antigen activity. T-antigen is present in many glycoconjugates such as M and N blood groups, gangliosides, and many other soluble and membrane-associated glycoproteins and glycolipids. PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase-treated red blood cells. The presence of Ca2+ can enhance the binding of PNA to receptors. A sialo GM1 ganglioside is also thought to be a major cell surface receptor for PNA. PNA is useful in normal and tumor tissue determination for transitional mucosa malignancies.
ApplicationsSuitable for use in Immunodiffusion and IEP. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide. Labeled with Biotin.
PurityPurified by ammonium sulfate precipitation.
ImmunogenArachis hypogaea (PNA, Peanut Agglutinin).
SpecificityRecognizes Arachis hypogaea (PNA, Peanut Agglutinin).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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