Anti -ARAP3 (Arf-GAP with Rho-GAP Domain, ANK Repeat and PH Domain-containing Protein 3,
Centaurin-delta-3, Cnt-d3, CENTD3)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| ARAP3, also known as Centaurin-delta-3, is a protein with an Arf-GAP domain, three PH domains, a Ras-associating domain, a Rho-GAP domain and a SAM (sterile alpha motif) domain. ARAP3 is a phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. It is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding and can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. ARAP3 acts on ARF6, RAC1, RHOA and CDC42 and also plays a role in the internalization of anthrax toxin. | | | Catalog # | A3309-10D | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: >1:4000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to CTSSPPSSQPLT, from the C-terminus of the protein sequence according to NP_071926. | | Specificity | Recognizes ARAP3. Species sequence homology: human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
