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You are here:Home » Antibodies » Abs to Apoptosis » Anti -ARC, CT (Activity-regulated Cytoskeleton-associated Protein, ARC/ARG3.1, Activity-regulated Gene 3.1 Protein Homolog, Arg3.1, KIAA0278)

Anti -ARC, CT (Activity-regulated Cytoskeleton-associated Protein, ARC/ARG3.1,
Activity-regulated Gene 3.1 Protein Homolog, Arg3.1, KIAA0278)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified IH
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and 8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Catalog #A3325-05B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human ARC at C-terminal (KLH).
SpecificityRecognizes human ARC.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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