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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -ARFBP1, CT (HUWE1, E3 Ubiquitin-protein Ligase HUWE1, ARF-binding Protein 1, ARF-BP1, HECT, UBA and WWE Domain-containing Protein 1, Homologous to E6AP Carboxyl Terminus Homologous Protein 9, HectH9, Large Structure of UREB1, LASU1, Mcl-1 Ubiquitin Ligase

Anti -ARFBP1, CT (HUWE1, E3 Ubiquitin-protein Ligase HUWE1, ARF-binding Protein 1,
ARF-BP1, HECT, UBA and WWE Domain-containing Protein 1, Homologous to E6AP Carboxyl
Terminus Homologous Protein 9, HectH9, Large Structure of UREB1, LASU1, Mcl-1 Ubiquitin
Ligase

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
HUWE1 is a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung, breast, and colorectal carcinomas, this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation, Turner type.
Catalog #A3330-12A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 19aa from human ARF-BP1 at C-terminal (KLH).
SpecificityRecognizes human ARF-BP1. Species sequence homology: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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