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Anti -ARG1 (Arginase-1, Liver-type Arginase, Type I Arginase)
Anti -ARG1 (Arginase-1, Liver-type Arginase, Type I Arginase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. | | | Catalog # | A3340-14A3 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilutions | Peptide ELISA: 1:2000 | | Western Blot: 0.03-0.1ug/ml. Band of ~35kD was observed in human liver lysates. Additional bands of unknown identity were also consistently observed at 19-22kD. These bands were successfully blocked by incubation with the immunizing peptide. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Liver lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-REGNHKPIDYLNPPK from the C-terminus of human ARG1 (NP_000036.2). | | Specificity | Recognizes human ARG1. Species sequence homology: canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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