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You are here:Home » Molecular Biology » MB-Enzymes » ARG2, aa23-354, Recombinant, Human (Arginase, Type II, Arginase-2, Mitochondrial, Kidney-type Arginase, Non-hepatic Arginase, Type II Arginase)

ARG2, aa23-354, Recombinant, Human (Arginase, Type II, Arginase-2, Mitochondrial,
Kidney-type Arginase, Non-hepatic Arginase, Type II Arginase)

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Specifications

Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. It is the final enzyme of the urea cycle. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic cross-reactivity and physiologic function. The type II isoform is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. It is thought to play a role in nitric oxide and polyamine metabolism.
Catalog #A3340-17H
Recombinant protein corresponding to aa23-354 of human ARG2 fused to a His-tag at the N-terminal expressed in E. coli (NP_001163).
AA SequencesMGSSHHHHHH SSGLVPRGSH MVHSVAVIGA PFSQGQKRKG VEHGPAAIRE AGLMKRLSSL GCHLKDFGDL SFTPVPKDDL YNNLIVNPRS VGLANQELAE VVSRAVSDGY SCVTLGGDHS LAIGTISGHA RHCPDLCVVW VDAHADINTP LTTSSGNLHG QPVSFLLREL QDKVPQLPGF
SWIKPCISSA SIVYIGLRDV DPPEHFILKN YDIQYFSMRD IDRLGIQKVM ERTFDLLIGK RQRPIHLSFD IDAFDPTLAP ATFTPVVGGL TYREGMYIAE EIHNTGLLSA LDLVEVNPQL ATSEEEAKTT ANLAVDVIAS SFGQTREGGH IVYDQLPTPS SPDESENQAR VRI
Molecular Weight 38.3kD (353aa), confirmed by MALDI-TOF
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight38.3kD
SourceE.coli
Purity~95% by SDS-PAGE. Purified using conventional chromatography techniques.
Concentration~0.5mg/ml
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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